The Spamhaus Exploits Block List (XBL) is a realtime database of IP addresses of hijacked PCs infected by illegal 3rd party exploits, including open proxies (HTTP, socks, AnalogX, wingate, etc), worms/viruses with built-in spam engines, and other types of trojan-horse exploits.
If your IP address is listed by the XBL, see the XBL FAQs for solutions