There are various reasons that can cause the error, such as other general operations in QuickBooks, activating or running payroll requiring you to run QuickBooks as an administrator and, if you are not using an proper account with appropriate admin rights, you will probably ace issues like QuickBooks Desktop error 40001. Other factors include pretty apparent that corruption in the company file, some technical glitches between the program and the Intuit server, the Company Realm ID of your QuickBooks Desktop not matching what Intuit has on their end, or if the installation of the QuickBooks Desktop been messed up due to some other program or accidental removal of QuickBooks program files, then also you can come across error code 40001 of QuickBooks.
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