Yes, third-party applications can potentially cause QuickBooks Error Code 6130. This error arises when there's an issue with opening or accessing a company file in QuickBooks. While Error Code 6130 is often associated with a corrupted or damaged company file, third-party applications such as antivirus or security software can inadvertently interfere with QuickBooks operations.

These applications might mistakenly identify QuickBooks files as potential threats and quarantine or block access to them, leading to Error Code 6130. To address this, consider temporarily disabling or adjusting the settings of third-party security applications to see if they are contributing to the error.

It's important to note that while third-party applications can contribute to QuickBooks Error Code 6130, other factors like network problems or file corruption can also be at play. Proper troubleshooting, including examining third-party software interactions, can help determine the root cause and resolve the error effectively.

Run the QuickBooks File Doctor tool or speak with QuickBooks support just dial us at +1(855)-738-0359.if the problem doesn't go away if you do any of those things.